Trent Brown, Shaq Mason, and Shaun Wade ruled out for Sunday’s Patriots-Texans game

Trent Brown, Shaq Mason, and Shaun Wade ruled out for Sunday

The Patriots, who were already thin at offensive line, will have to adjust once again.

Trent Brown (77) and Shaq Mason (69) are out Sunday. Jim Davis/Globe Staff

The Patriots will be without offensive tackle Trent Brown (calf), guard Shaq Mason (abdomen), and cornerback Shaun Wade (concussion) when they face the Houston Texans on Sunday.

Left tackle Isaiah Wynn and left guard Michael Onwenu are both on the COVID-19 reserve list, and their status for Sunday is in jeopardy. Regardless of whether or not they play, the Patriots will be thin at offensive line with Brown and Mason out. It’s possible center David Andrews could be the only starter.

Linebacker Ja’Whaun Bentley (shoulder), defensive back Cody Davis (knee), safety Kyle Dugger (hamstring), kicker Nick Folk (left knee), cornerback Jonathan Jones (ankle), defensive back Jalen Mills (hamstring), linebacker Ronnie Perkins (ankle), and linebacker Kyle Van Noy (groin) have all been limited throughout the week and are officially questionable.

Former Patriot Rex Burkhead (hip) is out, and fellow former Patriots Danny Amendola (thigh) and Marcus Cannon (back) are questionable.

Patriots ruled out right guard Shaq Mason (abdomen) and right tackle Trent Brown (right calf) for Sunday’s game vs. Texans, and left tackle Isaiah Wynn and left guard Mike Onwenu remain on the COVID-19 reserve list, per @MikeReiss. Center David Andrews is only Pats’ starter left.

— Adam Schefter (@AdamSchefter) October 8, 2021

The 1-3 Patriots are in desperate need of a win before a key matchup with the Dallas Cowboys next weekend. They’re 8.5-point favorites against the 1-3 Texans as of Thursday, but life could be a lot more difficult for quarterback Mac Jones and Co. with such a banged-up offensive line.

Kickoff is set for 1 p.m. at NRG Stadium in Houston.