California’s largest wave of coronavirus is showing no signs of slowing and what happens over this Thanksgiving weekend could have a drastic impact on the trajectory the state takes in the coming weeks.

California on Wednesday recorded 13,627 new coronavirus cases and an additional 101 lives lost due to COVID-19, according to data compiled by this news organization.

The state’s average number of new daily cases reached an all-time high once again — 13,621 per day over the past week — and 513 Californians have perished from COVID-19 this week, or an average of about 73 per day. Compared to two weeks ago, California’s average daily case count and death toll have more than doubled — and hospitalizations are similarly surging.

More Californians are hospitalized with COVID-19 than at any point since Aug. 6, according to the latest data from the California Department of Public Health. The surge in hospitalizations is the result of an uptick in cases that began around the end of October and now health officials fear the upward trajectory could continue exploding following the Thanksgiving holiday, pushing many areas of California to their hospital bed capacities.

The percentage of coronavirus tests returning positive results had reached nearly 6% again — up two points in the past two weeks but still below many other parts of the country.

The Bay Area added 1,760 new coronavirus cases on Wednesday and 10 additional lives to its death toll — three people died in both Santa Clara and Alameda counties and two in both Contra Costa and San Francisco counties.

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Santa Clara recorded 446 new cases on Wednesday — more than triple the number of cases reported in a day just one month ago. According to the county’s latest data, Santa Clara County has 302 hospital beds available and just 48 ICU beds.

Along with public health officials up and down the state, Santa Clara County officials have been holding news briefings almost daily the past week urging residents not to gather nor travel for the holiday weekend “period.”

“We absolutely need everyone to come together here in Santa Clara County right now for this Thanksgiving to do our collective part to stem this COVID-19 surge,” County Counsel James Williams said Wednesday.

San Mateo Public Health Officer Scott Marrow wrote in a statement this week that the holidays were a “critical time” to not let the state’s upward trend in cases, deaths and hospitalizations continue.

“While there is an enormous infrastructure stood up to try to protect you, if you don’t pay attention to your own actions, you will not like what is to come and how it will impact the people you care about,” he wrote.

Nationally, this week there has been an average of 176,733 new cases recorded per day — an increase of 38 percent from the average two weeks earlier, according to the New York Times COVID-19 data tracker. The country’s death toll has risen to more than 262,000 — the most of any country in the world by far — with deaths rising 57% in the past two weeks.